One time I was like pretty sure I had finally figured out that I had Symptoms Disease due to all the Symptoms and my doctor did some tests and she was like. Good news! You don't have Symptoms Disease!
And I started crying and she was like, is there something in your eye? And I said no I'm crying? And she was like, oh? Why? And I said, because we can't fix my Symptoms because we still don't know what's wrong with me? And she was like. Nothing's wrong with you! :)
Actually something similar had happened to me multiple times (and in some of those cases I did in fact get diagnosed with the relevant Symptoms Disease years later) but the one where the doctor asked if I had something in my eye because she couldn't comprehend that not having answers would be upsetting, that was definitely one of the most situations ever.